Portal Hypertension as Immune Mediate Disease

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Portal Hypertension as Immune Mediate Disease

CONTEXT Portal Hypertension (PH) is a progressive complication due to chronic liver disease. In addition to pathophysiologic changes in the micro-circulation, in PH are established fibrous tissue (periportal fibrous septal) and regenerative hyperplastic nodules (from micro- to macro-nodules) promoting hepatic architectural distortion. EVIDENCE ACQUISITION A literature search of electronic dat...

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Gauchers disease presenting with portal hypertension.

Gauchers disease is a rare lysosomal storage disorder characterized by abnormal accumulation of lipid-laden macrophages in different organs. Though hepatosplenomegaly is commonly found, symptomatic presentation with portal hypertension is rare. We report a child with liver cirrhosis and bleeding esophageal varices who was diagnosed with Gaucher's disease.

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Portal circulation and portal hypertension.

During the last 25 years, there have been important developments in visualising the portal vein, in examining its contents, and in measuring the pressure of blood flowing within it. Radiologists have set the scene and now is the time of the scanner. These technical advances have been applied to the diagnosis and treatment of patients with portal hypertension, and many ingenious surgical techniq...

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SURGICAL EXPERIENCE WITH PORTAL HYPERTENSION DUE TO HEPATOPORTAL SCLEROSIS (NONCIRRHOTIC PORTAL FIBROSIS)

Hepatoportal sclerosis or idiopathic portal hypertension has a worldwide distribution with prevalence in developing and temperate countries. Of 64 patients with this disease seen during a twelve year period, 36 underwent splenectomy or a shunt procedure. The indications for surgical intervention were severe hypersplenism and persistent left upper abdominal pain andlorhistory of frequent ep...

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Portal Hypertension

Introduction Portal hypertension (PHT) may be caused by a wide variety of conditions, each with a different natural history. It frequently presents with bleeding from oesophageal varices, which is the commonest cause of serious upper gastrointestinal haemorrhage in children. Precise diagnosis, a sound understanding of the therapeutic options, and a multidisciplinary approach are essential for s...

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ژورنال

عنوان ژورنال: Hepatitis Monthly

سال: 2014

ISSN: 1735-143X,1735-3408

DOI: 10.5812/hepatmon.18625